Friends of Santo's family said the North Side icon lapsed into a coma on Wednesday before dying Thursday. Santo died of complications from bladder cancer, WGN-AM 720 reported.
"He absolutely loved the Cubs," said Santo's broadcast partner, Pat Hughes. "The Cubs have lost their biggest fan."
Hughes noted that with all the medical problems Santo had--including diabetes with resulting leg amputations, his heart and bladder cancer--"he never complained. He wanted to have fun. He wanted to talk baseball."
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